Open Access Open Access  Restricted Access Subscription or Fee Access

Antagonistic Effects of Coral Reef Associated Bacteria from South Eastern India

C. Chellaram, T. Prem Anand


The bacteria isolated from the surface of the corals were found to have an inhibitory effect against 10 human pathogens. It was observed that out of 318 and 345 bacterial strains isolated from the surface of Favites abdita and Turbinaria mesenterina respectively, 12% was found be potent producers with maximum inhibition against Staphyloccus aureus (6 mm) and Streptococcus pneumonia (6 mm). It was observed in that the same percentage (12%) of bacterial strains isolated from Turbinaria mesenterina. Gram-positive, Gram-negative, pigmented and non-pigmented strains were all found to be antibiotic producers without exceptions. However, the antibiotic producing strains consisted of a higher percentage of non-pigmented strains in comparison with that of the pigmented ones, Favites abdita (38/288 strains), Turninaria mesenterina (41/304 strains). These results suggest that the epiphytic bacteria isolated from these corals could be effectively used for the development of novel drugs to combat the pathogens producing diseases to humans.


Corals, Marine Bacteria, Antagonistic Activity, Human Pathogens

Full Text:



Anand T P. Screening for bioactive metabolites producing bacteria from Tuticorin coastal waters, South east coast of India, Ph. D thesis, Manonmaniam Sundaranar University, India, 2002.

Chellaram C., Gnanambal. K. M. E and Edward. J. K. P. 2004. Antibacterial activity of the winged oyster, Pteria chinensis (Pterioida: Pteridae). Indian J. Mar. Sci. 33 (4): 369 -372.

Chellaram, C and J K P. Edward, 2009. Anti-nocicetive Assets of Coral Associated Gastropod, Drupa margariticola. Int. J. Pharmacol. 5 (3): 236 –239

Chelossi E, Milanese M, Milano A, Pronzato R & Riccardi G. 2004. Characterization and antimicrobial activity of epibiotic bacteria from Petrosia ficiformis (Porifera, Demospongiae), J Exp Mar Biol Ecol, 309: 21-33.

Dobretsov, S and Qian, P. 2004. The role of epibiotic bacteria from the surface of the soft coral, Dendronephthya sp. in the inhibition of larval settlement. J. Exp. Mar. Biol. Ecol. 299: 35-50

Dopazo C P, Lemos M L, Lodeiros C, Bolinches J, Barja J L and Toranzo A E. 1988. Inhibitory activity of antibiotic producing marine bacteria against the fish pathogens, J Appl Bacteriol, 65:97-101.

Ducklow H W and Mitchell R. 1979. Bacterial population and adaptations in the mucous layers on living corals, Limnol Oceanogr, 24: 715-725.

Fenical W. 1993. Chemical studies of marine bacteria: Developing a new resource, Chem Rev, 93: 1673-1683.

Gauthier M J. 1976. Modification of the bacterial respiration by a polyanionic antibiotic produced by a marine Alteromonas, Antimicrob Agents Chemother, 9: 349-354.

Jayanth K, Jeyasekaran G & Jeya Shakila R, Isolation of marine bacteria, antagonistic to human pathogens, Indian J Mar Sci, 31 (2002) 39-44.

Lemos, M. L., Toranzo, A. E and Barja, J. L. 1985. Antibiotic activity of epiphytic bacteria isolated from inter-tidal seaweeds. Microbial. Ecol. 11: 149-163

Patil, R., Jeyasekaran, G., Shanmugam, S. A and Shakila, R. J. 2001. Control of bacterial pathogens, associated with fish diseases, by antagonistic marine actinomycetes isolated from marine sediments. Indian J. Mar. Sci. 30 (4): 264-267

Rosenfeld WD and Zobell CE. 1947. Antibiotic production by the marine microorganisms, J. Bacteriol, 54: 393-398

Zheng Z, Zeng W, Huang Y, Yang Z, Li J, Cai H and Su W. 2000. Detection of anti-tumor and antimicrobial activities in marine organisms associated Actinomycetes isolated from the Taiwan Strait, China, FEMS Microbiol Lett, 87-91.


  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.