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Detection of Microcalcification in Digital Mammograms Using Multi-Scale Products and Active Contour Model

T. Balakumaran, Dr. ILA. Vennila, C. Gowrishankar

Abstract


Mammography is the most efficient method for breast cancer early detection. Clusters of microcalcifications are the early sign of breast cancer and their detection is the key to improve prognosis of breast cancer. Microcalcifications appear in mammogram image as tiny localized granular points, which is often difficult to detect by naked eye because of their small size.  Automatic and accurately detection of microcalcifications has received much more attention from radiologists and physician. An efficient method for automatic detection of clustered microcalcifications in digitized mammograms is the use of Computer Aided Diagnosis (CAD) systems. This paper presents a two dimensional wavelet-based multiscale products scheme for microcalcification detection in mammogram images. Initially, Mammogram image was decomposed by 2D wavelet transform into different frequency sub-bands, the low-frequency subband was suppressed and significant high frequencies features were reconstructed. The significant high frequencies features were obtained by multiscale products. An Active contour model was applied on reconstructed image and microcalcification nodules were segmented from resulting image. Preliminary results indicate that the proposed scheme is better in suppressing the background and detecting the microcalcification clusters.


Keywords


Active Contour Model, Computer Aided Diagnosis (CAD), Multiscale Product, Microcalcification Detection

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References


P.Heinlein, J.Drexl, and W.Schneider, “Integrated Wavelet for enhancement of Microcalcification in Digital mammography,” IEEE Transaction on medical imaging, Vol.22,pp. 402-413, Mar. 2003.

Nakayama, R. Uchiyama, Y. Yamamoto, K.Watanabe, and R. Namba, K, “Computer-aided Diagnosis scheme using a filter bank for detection of microcalcification clusters in mammograms”, IEEE Transactions on Biomedical Engineering, vol 53.No.2,p.273-283, Feb. 2006

R. G. Bird, T. W. Wallace, and B. C. Yankaskas, “Analysis of cancers missed at screening mammography,” Radiology, vol. 184, pp. 613– 617,1992

H. Burhenne, L. Burhenne, F. Goldberg, T. Hislop, A. J. Worth, P. M. Rebbeck, and L. Kan, “Interval breast cancers in the screening mammography program of British Columbia: Analysis and classification,” Am. J. Roentgenol., vol. 162, pp.1067-1071,1994.

H. P. Chan, K. Doi, C. J. Vyborny, K. L. Lam,and R. A. Schmidt, “Computer-aided detection of microcalcifications in mammograms: Methodology and preliminary clinical study,” Invest. Radiol., vol. 23,pp. 664–671,1988.

H. P. Chan, K. Doi, C. J. Vyborny, R. A.Schmidt, C. E. Metz, K. L. Lam, T. Ogura, Y. Z.Wu, and H. MacMahon, “Improvement in radiologists’ detection of clustered microcalcifications on mammograms. The potential of computer-aided diagnosis,” Invest. Radiol., vol. 25, pp. 1102–1110,1990

H. Yoshida, K. Doi, and R. M. Nishikawa,“Automated detection of clustered microcalcifications,” Proc. SPIE (Digital Mammograms UsingWavelet Transform Tech.,Med. Imag. 1994: Image Process.), vol. 2167, pp.868–886, Feb. 1994.

H. Yoshida, K. Doi, R. M. Nishikawa, M. L. Giger, and R. A. Schmidt, “An improved computer- Assisted diagnostic scheme using wavelet transform for detecting clustered microcalcifications in digital mammograms,”Acad Radiol., vol. 3, pp. 621–627,1996.

W. Qian, L. P. Clarke, B. Zheng, M. Kallergi, and R. A. Clark, “Computer assisted diagnosis for digital mammography,” IEEE Eng. Med. Biol. Mag., vol. 14,no.5, pp. 561–569, Sep.-Oct. 1995.

A.F. Laine, S. Schuler, J. Fan, and W. Huda,“Mammographic feature enhancement by multiscale analysis,” IEEE Trans. Med. Imag., vol. 13, no. 4, pp.725–740, Dec. 1994.

Ted C. Wang and Nicolaos B. Karayiannis,"Detection of Microcalcifications in Digital Mammograms Using Wavelets", IEEE Tran. On Medical Imaging, vol. 17 pp. 498- 509, Aug. 1998.

Damir Sersic and Sven Loncaric, "Enhancement of Mammographic Images for Detection of Microcalcifications", Fac.of Electrical Engineering and Computing, Zagreb, Croatia,1998.

Chun-Ming Chang and Andrew Laine,"Coherence of Multiscale Features for Enhancement of Digital Mammograms",IEEE Tran. On Information Technology in Biomedical, vol. 3, n1,pp. 32-46, 1999

Daubechies,“Orthonormal bases of Compactly Supported wavelets ,”Comm. Pure Appl. Math., vol.41, pp. 909-996,1988.

S.G.Mallat, “A theory for multiresolution Signal decomposition: the wavelet representation,” IEEE Trans.Pattern Anal. Machine Intell., vol. 11, no. 7,pp.674-693, June 1989.

J. Suckling et al. The Mammographic Image Analysis Society Digital Mammogram Database. Experta Medical International Congress Series, 1069, pp. 375-378,1994.

S.Mallat and W. L. Hwang, “Singularity Detection and processing with wavelets,” IEEE Transactions on Information Theory, vol.38,pp.617-643,1992

S. Bouyahia, J. Mbainaibeye, and N. Ellouze, “Characterisation of singularities by wavelet Transform modulus maxima : application to Microcalcifications detection in digitized mammograms,” 7th IASTED International Conference on Signal and Image Processing SIP 2005, Honolulu, Hawaii, August, 15-17, 2005

B. M. Sadler, and A. Swami, “Analysis of multi-Scale Products for step detection and estimation,” IEEE Transactions on Information Theory, vol. 45,pp.1043-1051,1999

S.Mallat and S.Zhong, “Characterization of Signals from multiscale edges,” IEEE Trans. Pattern Anal.Machine Intell., vol. 14, pp 710-732, July 1992.

Y. Xu, J. B. Weaver, D. M. Healy Jr, and J. Lu,“Wavelet transform domain filters: A spatially Selective Noise filtration technique,” IEEE Trans.Image Processing, vol. 3, pp. 747–758, Nov.1994.

M. Kass, A. Witkin, and T. Terzopoulous. Snakes: Active contour models.International Journal of Computer Vision, pages 321-331, 1988.

J. A. Sethian, level set Methods and Fast Marching Methods, seconded.,Cambridge University Press, 1999.

V. Caselles, R. Kimmel, and G. Sapiro, Geodesic active contours," in Proceedings, International Journal of Computer Vision,pp. 61-79, 1997

T.F.Chan, and L.Vese – “Active Contours Without Edges,” IEEE Trans. Image. Proc., vol10(2) :266-277, 2001.

Luminita A. Vese and Tony F. Chan, A Multiphase Level Set Framework for Image Segmentation Using the Mumford and Shah Model,International Journal of Computer Vision 50(3), 271–293, 2002.


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